An original synthesis of the cited guides. Adjust the approach to your difficulty and equipment.
Identify what stops you
Use Altars of Reflection to expand your skill options, and visit Hot Springs and Bamboo Strikes to improve health and resolve. If a major duel blocks your progress, try nearby growth activities first.
Choose an upgrade
Check melee weapon upgrades at home, and bows and arrow capacity with Ran. Prioritize the equipment you use most to make the next fight easier with fewer materials.
Gather along your route
After clearing a camp, check reward chests and enemy loot. If you are short on a material, check whether its main region is accessible before repeatedly searching the same area.